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BMC Medicine

ISSN Print: 1741-7015

ISSN Online:

主页: http://www.biomedcentral.com/bmcmed

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The young osteoarthritic knee: dilemmas in management

Sutton Paul M,Holloway Edward S

Plasminogen activator inhibitor-1 4G/5G polymorphism and retinopathy risk in type 2 diabetes: a meta-analysis

Zhang Tengyue,Pang Chong,Li Ningdong,Zhou Elaine

Video Q&A: Excess body weight and cancer

Kaaks Rudolf

RAMESES publication standards: meta-narrative reviews

Wong Geoff,Greenhalgh Trish,Westhorp Gill,Buckingham Jeanette

Bariatric surgery: the challenges with candidate selection, individualizing treatment and clinical outcomes

Neff KJ,Olbers T,le Roux CW

Meta-analysis: implications of interleukin-28B polymorphisms in spontaneous and treatment-related clearance for patients with hepatitis C

Jiménez-Sousa María A,Fernández-Rodríguez Amanda,Guzmán-Fulgencio María,García-álvarez Mónica

Economic analyses to support decisions about HPV vaccination in low- and middle-income countries: a consensus report and guide for analysts

Jit Mark,Levin Carol,Brisson Marc,Levin Ann

Diet, a new target to prevent depression?

Sanchez-Villegas Almudena,Martínez-González Miguel A

RAMESES publication standards: realist syntheses

Wong Geoff,Greenhalgh Trish,Westhorp Gill,Buckingham Jeanette

Multigenerational epigenetic effects of nicotine on lung function

Leslie Frances M

Fat dads must not be blamed for their children's health problems

Moore Gudrun E,Stanier Philip

Paternal obesity is associated with IGF2 hypomethylation in newborns: results from a Newborn Epigenetics Study (NEST) cohort

Soubry Adelheid,Schildkraut Joellen M,Murtha Amy,Wang Frances

How well do clinical prediction rules perform in identifying serious infections in acutely ill children across an international network of ambulatory care datasets?

Verbakel Jan Y,Van den Bruel Ann,Thompson Matthew,Stevens Richard

Recent advances in the diagnosis and treatment of bladder cancer

Cheung Grace,Sahai Arun,Billia Michele,Dasgupta Prokar

Clinical development of monoclonal antibody-based drugs in HIV and HCV diseases

Flego Michela,Ascione Alessandro,Cianfriglia Maurizio,Vella Stefano

Genetics of scleroderma: implications for personalized medicine?

Assassi Shervin,Radstake Timothy RDJ,Mayes Maureen D,Martin Javier

Support of personalized medicine through risk-stratified treatment recommendations - an environmental scan of clinical practice guidelines

Yu Tsung,Vollenweider Daniela,Varadhan Ravi,Li Tianjing

Epigenetic mechanisms in migraine: a promising avenue?

Eising Else,A Datson Nicole,van den Maagdenberg Arn MJM,Ferrari Michel D

Recent findings on the health effects of omega-3 fatty acids and statins, and their interactions: do statins inhibit omega-3?

de Lorgeril Michel,Salen Patricia,Defaye Pascal,Rabaeus Mikael

Collectives of diagnostic biomarkers identify high-risk subpopulations of hematuria patients: exploiting heterogeneity in large-scale biomarker data

Emmert-Streib Frank,Abogunrin Funso,de Matos Simoes Ricardo,Duggan Brian

Fasudil improves survival and promotes skeletal muscle development in a mouse model of spinal muscular atrophy

Melissa Bowerman, Lyndsay M Murray, Justin G Boyer, Carrie L Anderson, Rashmi Kothary

Rest versus exercise as treatment for patients with low back pain and Modic changes. a randomized controlled clinical trial

Rikke K Jensen, Charlotte Leboeuf-Yde, Niels Wedderkopp, Joan S Sorensen, Claus Manniche

Viruses exacerbating chronic pulmonary disease: the role of immune modulation

Aran Singanayagam, Priya V Joshi, Patrick Mallia, Sebastian L Johnston

The effects of multi-domain versus single-domain cognitive training in non-demented older people: a randomized controlled trial

Yan Cheng, Wenyuan Wu, Wei Feng, Jiaqi Wang, You Chen, Yuan Shen, Qingwei Li, Xu Zhang, Chunbo Li

Lifestyle interventions for overweight and obese pregnant women to improve pregnancy outcome: systematic review and meta-analysis

Eugene Oteng-Ntim, Rajesh Varma, Helen Croker, Lucilla Poston, Pat Doyle

The role of nutrition in integrated programs to control neglected tropical diseases

Andrew Hall, Yaobi Zhang, Chad MacArthur, Shawn Baker

Insufficient maintenance DNA methylation is associated with abnormal embryonic development

Li-Jun Yin, Yu Zhang, Ping-Ping Lv, Wei-Hua He, Yan-Ting Wu, Ai-Xia Liu, Guo-Lian Ding, Min-Yue Dong, Fan Qu, Chen-Ming Xu, Xiao-Ming Zhu, He-Feng Huang

Transcriptome changes in age-related macular degeneration

S Scott Whitmore, Robert F Mullins

Mitochondrial aldehyde dehydrogenase (ALDH2) protects against streptozotocin-induced diabetic cardiomyopathy: role of GSK3β and mitochondrial function

Yingmei Zhang, Sara A Babcock, Nan Hu, Jacalyn R Maris, Haichang Wang, Jun Ren

Systematic review and meta-analysis of the value of initial biomarkers in predicting adverse outcome in febrile neutropenic episodes in children and young people with cancer

Robert S Phillips, Ros Wade, Thomas Lehrnbecher, Lesley A Stewart, Alex J Sutton

Targeting the epidermal growth factor receptor in non-small cell lung cancer cells: the effect of combining RNA interference with tyrosine kinase inhibitors or cetuximab

Gang Chen, Peter Kronenberger, Erik Teugels, Ijeoma Umelo, Jacques De Grève

The Transeurope Footrace Project: longitudinal data acquisition in a cluster randomized mobile MRI observational cohort study on 44 endurance runners at a 64-stage 4,486km transcontinental ultramarathon

Uwe HW Schütz, Arno Schmidt-Trucks？ss, Beat Knechtle, Jürgen Machann, Heike Wiedelbach, Martin Ehrhardt, Wolfgang Freund, Stefan Gr？ninger, Horst Brunner, Ingo Schulze, Hans-Jürgen Brambs, Christian Billich

Metabolic profiling detects early effects of environmental and lifestyle exposure to cadmium in a human population

James K Ellis, Toby J Athersuch, Laura DK Thomas, Friederike Teichert, Miriam Pérez-Trujillo, Claus Svendsen, David J Spurgeon, Rajinder Singh, Lars J？rup, Jacob G Bundy, Hector C Keun

The effectiveness of neuromuscular warm-up strategies, that require no additional equipment, for preventing lower limb injuries during sports participation: a systematic review

Katie Herman, Christian Barton, Peter Malliaras, Dylan Morrissey

Access to preventive care by immigrant populations

Mark Harris

Novel regulatory therapies for prevention of Graft-versus-host disease

Joseph Leventhal, Yiming Huang, Hong Xu, Idona Goode, Suzanne T Ildstad

Effects of phlebotomy-induced reduction of body iron stores on metabolic syndrome: results from a randomized clinical trial

Khosrow S Houschyar, Rainer Lüdtke, Gustav J Dobos, Ulrich Kalus, Martina Broecker-Preuss, Thomas Rampp, Benno Brinkhaus, Andreas Michalsen

Does the oxytocin receptor polymorphism (rs2254298) confer 'vulnerability' for psychopathology or 'differential susceptibility'? insights from evolution

Martin Brüne

Clinical evaluation of iron treatment efficiency among non-anemic but iron-deficient female blood donors: a randomized controlled trial

Sophie Waldvogel, Baptiste Pedrazzini, Paul Vaucher, Raphael Bize, Jacques Cornuz, Jean-Daniel Tissot, Bernard Favrat

Resitting a high-stakes postgraduate medical examination on multiple occasions: nonlinear multilevel modelling of performance in the MRCP(UK) examinations

IC McManus, Katarzyna Ludka

Crosstalk between HIV and hepatitis C virus during co-infection

Paul J Rider, Fenyong Liu

Zinc adjunct therapy reduces case fatality in severe childhood pneumonia: a randomized double blind placebo-controlled trial

Maheswari G Srinivasan, Grace Ndeezi, Cordelia Mboijana, Sarah Kiguli, Gabriel S Bimenya, Victoria Nankabirwa, James K Tumwine

Outbreaks of virulent diarrheagenic Escherichia coli - are we in control?

Dirk Werber, Gérard Krause, Christina Frank, Angelika Fruth, Antje Flieger, Martin Mielke, Lars Schaade, Klaus Stark

Development and description of measurement properties of an instrument to assess treatment burden among patients with multiple chronic conditions

Viet-Thi Tran, Victor M Montori, David T Eton, Dan Baruch, Bruno Falissard, Philippe Ravaud

Therapy for metastatic melanoma: the past, present, and future

Laura Finn, Svetomir N Markovic, Richard W Joseph

Mirroring everyday clinical practice in clinical trial design: a new concept to improve the external validity of randomized double-blind placebo-controlled trials in the pharmacological treatment of major depression

Emanuel Severus, Florian Seemüller, Michael Berger, Sandra Dittmann, Michael Obermeier, Andrea Pfennig, Michael Riedel, Sophia Frangou, Hans-Jürgen M？ller, Michael Bauer

Cost-effectiveness analysis for clinicians

Suzanne R Hill

Diindolylmethane suppresses ovarian cancer growth and potentiates the effect of cisplatin in tumor mouse model by targeting signal transducer and activator of transcription 3 (STAT3)

Prabodh K Kandala, Sanjay K Srivastava

Comparative effectiveness of antihypertensive medication for primary prevention of cardiovascular disease: systematic review and multiple treatments meta-analysis

Atle Fretheim, Jan Odgaard-Jensen, Odd Br？rs, Steinar Madsen, Inger Nj？lstad, Ole F Norheim, Arne Svilaas, Ivar S Kristiansen, Hanne Thürmer, Signe Flottorp

Born to run. Studying the limits of human performance

Andrew Murray, Ricardo J.S. Costa

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