全部 标题 作者
关键词 摘要

OALib Journal期刊
ISSN: 2333-9721
费用：99美元
投递稿件

为什么选择我们？ >>
- 开源期刊
- 同行审议
- 快速出刊
- 终身存储
- 免费检索
- 免费推广
- 更多...
- 搜索引擎

-

ISSN Print:

ISSN Online:

主页: https://pubs.acs.org/journal/acbcct

分享:




Go

Toward Single-Peak Dalbavancin Analogs through Biology and Chemistry

Leukemia Cell Cycle Chemical Profiling Identifies the G2-Phase Leukemia Specific Inhibitor Leusin-1

Glycated Insulin Exacerbates the Cytotoxicity of Human Islet Amyloid Polypeptides: a Vicious Cycle in Type 2 Diabetes

Understanding the Contributions of Conformational Changes, Thermodynamics, and Kinetics of RNA–Small Molecule Interactions

NMR Dynamics Study Reveals the Zα Domain of Human ADAR1 Associates with and Dissociates from Z-RNA More Slowly than Z-DNA

CB-6644 Is a Selective Inhibitor of the RUVBL1/2 Complex with Anticancer Activity

Condensation-Incompetent Ketosynthase Inhibits trans-Acyltransferase Activity

Slt, MltD, and MltG of Pseudomonas aeruginosa as Targets of Bulgecin A in Potentiation of β-Lactam Antibiotics

Evolutionary Trajectories for the Functional Diversification of Anthracycline Methyltransferases

Targeting Base Excision Repair Glycosylases with DNA Containing Transition State Mimics Prepared via Click Chemistry

Small Molecule and Pooled CRISPR Screens Investigating IL17 Signaling Identify BRD2 as a Novel Contributor to Keratinocyte Inflammatory Responses

Peptidoglycan Metabolite Photoaffinity Reporters Reveal Direct Binding to Intracellular Pattern Recognition Receptors and Arf GTPases

Detecting Secretory Proteins by Acoustic Droplet Ejection in Multiplexed High-Throughput Applications

Previously Uncharacterized Vacuolar-type ATPase Binding Site Discovered from Structurally Similar Compounds with Distinct Mechanisms of Action

Covalent Modifiers of Botulinum Neurotoxin Counteract Toxin Persistence

Biosynthesis and Chemical Applications of Thioamides

SPR-Measured Dissociation Kinetics of PROTAC Ternary Complexes Influence Target Degradation Rate

Unique Polypharmacology Nuclear Receptor Modulator Blocks Inflammatory Signaling Pathways

Kinetics of d-Amino Acid Incorporation in Translation

Toolbox of Diverse Linkers for Navigating the Cellular Efficacy Landscape of Stapled Peptides

A Phenotypic Screening Approach Using Human Treg Cells Identified Regulators of Forkhead Box p3 Expression

PROTAC-Mediated Degradation of Bruton’s Tyrosine Kinase Is Inhibited by Covalent Binding

GLI1-Inducible Glucuronidation Targets a Broad Spectrum of Drugs

A Unified Framework for the Incorporation of Bioorthogonal Compound Exposure Probes within Biological Compartments

Selective PKCδ Inhibitor B106 Elicits Uveal Melanoma Growth Inhibitory Effects Independent of Activated PKC Isoforms

N-Acyl Homoserine Lactone Derived Tetramic Acids Impair Photosynthesis in Phaeodactylum tricornutum

Activity-Based Protein Profiling Identifies α-Ketoamides as Inhibitors for Phospholipase A2 Group XVI

Double Nitroxide Labeling by Copper-Catalyzed Azide–Alkyne Cycloadditions with Noncanonical Amino Acids for Electron Paramagnetic Resonance Spectroscopy

A trans-Acting Cyclase Offloading Strategy for Nonribosomal Peptide Synthetases

Transient Compound Treatment Induces a Multigenerational Reduction of Oxysterol-Binding Protein (OSBP) Levels and Prophylactic Antiviral Activity

Transferrin Cycle and Clinical Roles of Citrate and Ascorbate in Improved Iron Metabolism

Rapid and Reversible Knockdown of Endogenously Tagged Endosomal Proteins via an Optimized HaloPROTAC Degrader

Selective Small-Molecule Targeting of a Triple Helix Encoded by the Long Noncoding RNA, MALAT1

Chemical Diversification Based on Substrate Promiscuity of a Standalone Adenylation Domain in a Reconstituted NRPS System

Site-Specifically Studying Lysine Acetylation of Aminoacyl-tRNA Synthetases

Esterase-Triggered Self-Immolative Thiocarbamates Provide Insights into COS Cytotoxicity

Development of a Nitric Oxide-Responsive Labeling Reagent for Proteome Analysis of Live Cells

Crystal Structures of Fumarate Hydratases from Leishmania major in a Complex with Inhibitor 2-Thiomalate

Directed Evolution of Split APEX2 Peroxidase

Reverse Chemical Proteomics Identifies an Unanticipated Human Target of the Antimalarial Artesunate

Class I Methyltransferase VioH Catalyzes Unusual S-Adenosyl-l-methionine Cyclization Leading to 4-Methylazetidinecarboxylic Acid Formation during Vioprolide Biosynthesis

Novel Methoxymethacrylate Natural Products Uncovered by Statistics-Based Mining of the Myxococcus fulvus Secondary Metabolome

DNA-Encoded Library-Derived DDR1 Inhibitor Prevents Fibrosis and Renal Function Loss in a Genetic Mouse Model of Alport Syndrome

Biosynthetic Basis for Structural Diversity of Aminophenylpyrrole-Derived Alkaloids

Efficient Intracellular Delivery of CRISPR-Cas Ribonucleoproteins through Receptor Mediated Endocytosis

Peptide-Membrane Interactions Affect the Inhibitory Potency and Selectivity of Spider Toxins ProTx-II and GpTx-1

A Cancer-Selective Zinc Ionophore Inspired by the Natural Product Naamidine A

Improving Selectivity, Proteolytic Stability, and Antitumor Activity of Hymenochirin-1B: A Novel Glycosylated Staple Strategy

Engineering Atypical Tetracycline Formation in Amycolatopsis sulphurea for the Production of Modified Chelocardin Antibiotics

Small Molecule SOS1 Agonists Modulate MAPK and PI3K Signaling via Independent Cellular Responses

Go




©2008-2017 OALib, Inc | Public user content licensed CC-BY 4.0 unless otherwise specified. OALib ISSN Online: 2333-9721 OALib ISSN Print: 2333-9705