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OALib Journal期刊
ISSN: 2333-9721
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An Excitatory Circuit in the Perioculomotor Midbrain for Non-REM Sleep Control

A Forward Chemical Genetic Screen Reveals Gut Microbiota Metabolites That Modulate Host Physiology

Structural Insights into the Process of GPCR-G Protein Complex Formation

Self-Organized Nuclear Positioning Synchronizes the Cell Cycle in Drosophila Embryos

Structure and Degradation of Circular RNAs Regulate PKR Activation in Innate Immunity

Deficient Endoplasmic Reticulum-Mitochondrial Phosphatidylserine Transfer Causes Liver Disease

Selenium Drives a Transcriptional Adaptive Program to Block Ferroptosis and Treat Stroke

Ripretinib (DCC-2618) Is a Switch Control Kinase Inhibitor of a Broad Spectrum of Oncogenic and Drug-Resistant KIT and PDGFRA Variants

The Direct Molecular Target for Imipridone ONC201 Is Finally Established

CD40 Ligand-Modified Chimeric Antigen Receptor T Cells Enhance Antitumor Function by Eliciting an Endogenous Antitumor Response

Waun Ki Hong (1942–2019) John Mendelsohn (1936–2019)

CHD1 Loss Alters AR Binding at Lineage-Specific Enhancers and Modulates Distinct Transcriptional Programs to Drive Prostate Tumorigenesis

Pervasive H3K27 Acetylation Leads to ERV Expression and a Therapeutic Vulnerability in H3K27M Gliomas

Combination of Hypoglycemia and Metformin Impairs Tumor Metabolic Plasticity and Growth by Modulating the PP2A-GSK3β-MCL-1 Axis

Serine and Methionine Metabolism: Vulnerabilities in Lethal Prostate Cancer

Therapeutic Clues from an Integrated Omic Assessment of East Asian Triple Negative Breast Cancers

The Perfect Appetizer: A Pharmacological Strategy for a Non-biting Mosquito

Environmental Control of Astrocyte Pathogenic Activities in CNS Inflammation

Sub-nucleosomal Genome Structure Reveals Distinct Nucleosome Folding Motifs

UBQLN4 Represses Homologous Recombination and Is Overexpressed in Aggressive Tumors

Self-Maintaining Gut Macrophages Are Essential for Intestinal Homeostasis

The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest

Genomic Analysis in the Age of Human Genome Sequencing

Human Immunology through the Lens of Evolutionary Genetics

Genetics of Common, Complex Coronary Artery Disease

Global Genetic Networks and the Genotype-to-Phenotype Relationship

Gene-Environment Interaction in the Era of Precision Medicine

Personalized Medicine and the Power of Electronic Health Records

Local Determinants of the Mutational Landscape of the Human Genome

Human Tumor-Associated Macrophage and Monocyte Transcriptional Landscapes Reveal Cancer-Specific Reprogramming, Biomarkers, and Therapeutic Targets

Capitalizing on Cancer Replication Stress by Preventing PAR Chain Turnover: A New Type of Synthetic Lethality

Molecular Classification and Comparative Taxonomics of Foveal and Peripheral Cells in Primate Retina

Identification of Enteroendocrine Regulators by Real-Time Single-Cell Differentiation Mapping

Sexually Dimorphic Control of Parenting Behavior by the Medial Amygdala

Plasticity of the Electrical Connectome of C. elegans

Structural Basis of Nav1.7 Inhibition by a Gating-Modifier Spider Toxin

FXR Regulates Intestinal Cancer Stem Cell Proliferation

CCR5 Is a Therapeutic Target for Recovery after Stroke and Traumatic Brain Injury

Regulation of MicroRNA Machinery and Development by Interspecies S-Nitrosylation

Molecular Discrimination between Two Conformations of Sphingomyelin in Plasma Membranes

γ-Catenin-Dependent Signals Maintain BCR-ABL1+ B Cell Acute Lymphoblastic Leukemia

The Oncogenic Transcription Factor RUNX1/ETO Corrupts Cell Cycle Regulation to Drive Leukemic Transformation

Evolutionary Trajectories of IDHWT Glioblastomas Reveal a Common Path of Early Tumorigenesis Instigated Years ahead of Initial Diagnosis

Does Autophagy Promote Longevity? It Depends.

Counting Calories: The Cost of Inflammation

Explicating Exosomes: Reclassifying the Rising Stars of Intercellular Communication

Metabolic and Innate Immune Cues Merge into a Specific Inflammatory Response via the UPR

A Site of Vulnerability on the Influenza Virus Hemagglutinin Head Domain Trimer Interface

Small RNA Sequencing across Diverse Biofluids Identifies Optimal Methods for exRNA Isolation

A Diagnosis for All Rare Genetic Diseases: The Horizon and the Next Frontiers

©2008-2017 OALib, Inc | Public user content licensed CC-BY 4.0 unless otherwise specified. OALib ISSN Online: 2333-9721 OALib ISSN Print: 2333-9705