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OALib Journal期刊
ISSN: 2333-9721
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ISSN Print: 1476-5462

ISSN Online:

主页: https://www.nature.com/gt

Astrocyte-selective AAV gene therapy through the endogenous GFAP promoter results in robust transduction in the rat spinal cord following injury

Regulatable adenovector harboring the GFP and Yamanaka genes for implementing regenerative medicine in the brain

Inhibition of microRNA-495 suppresses chondrocyte apoptosis through activation of the NF-κB signaling pathway by regulating CCL4 in osteoarthritis

Safe and neuroprotective vectors for long-term traumatic brain injury gene therapy

Helper-dependent adenovirus-mediated gene transfer of a secreted LDL receptor/transferrin chimeric protein reduces aortic atherosclerosis in LDL receptor-deficient mice

A novel xenograft mouse model for testing approaches targeting human kappa light-chain diseases

Combination of cabazitaxel and p53 gene therapy abolishes prostate carcinoma tumor growth

Adeno-associated virus neutralising antibodies in type 1 diabetes mellitus

Delivering cellular and gene therapies to patients: solutions for realizing the potential of the next generation of medicine

Magic realism: a Latin American paradigm for stem cell research & development?

Gene and cell therapy on the acquisition and relapse-like binge drinking in a model of alcoholism: translational options

Measles vector as a multiple genes delivery platform facilitating iPSC reprogramming

Cell therapy for Parkinson′s disease is coming of age: current challenges and future prospects with a focus on immunomodulation

Safety and efficacy evaluations of an adeno-associated virus variant for preparing IL10-secreting human neural stem cell-based therapeutics

scFv6.C4 DNA vaccine with fragment C of Tetanus toxin increases protective immunity against CEA-expressing tumor

Polarized AAVR expression determines infectivity by AAV gene therapy vectors

Dual-targeted NIS polyplexes—a theranostic strategy toward tumors with heterogeneous receptor expression

Combination of cytokine-enhanced vaccine and chemo-gene therapy as surgery adjuvant treatments for spontaneous canine melanoma

Production of lentiviral vectors using novel, enzymatically produced, linear DNA

A novel approach for assessment of prostate cancer aggressiveness using survivin-driven tumour-activatable minicircles

Factors governing the transduction efficiency of adeno-associated virus in the retinal ganglion cells following intravitreal injection

Bat adeno-associated viruses as gene therapy vectors with the potential to evade human neutralizing antibodies

Regulated ex vivo regional gene therapy for bone repair using an inducible caspase-9 suicide gene system

ILK promotes survival and self-renewal of hypoxic MSCs via the activation of lncTCF7-Wnt pathway induced by IL-6/STAT3 signaling

Stability of the adeno-associated virus 8 reference standard material

Optimization of viral protein ratios for production of rAAV serotype 5 in the baculovirus system

Downreguation of FoxM1 by miR-214 inhibits proliferation and migration in hepatocellular carcinoma

HIV infection alters the human epigenetic landscape

Targeted in vivo knock-in of human alpha-1-antitrypsin cDNA using adenoviral delivery of CRISPR/Cas9

Effect of PAK1 gene silencing on proliferation and apoptosis in hepatocellular carcinoma cell lines MHCC97-H and HepG2 and cells in xenograft tumor

Electroporation-mediated delivery of FER gene enhances innate immune response and improves survival in a murine model of pneumonia

In vivo delivery of pPERDBY to BALB/c mice by LacVax？ DNA-I and comparison of elicited immune response with conventional immunization methods

Anti-angiogenic treatment of endometriosis via anti-VEGFA siRNA delivery by means of peptide-based carrier in a rat subcutaneous model

Unilateral ex vivo gene therapy by GDNF in epileptic rats

Understanding the molecular biology of intervertebral disc degeneration and potential gene therapy strategies for regeneration: a review

Serotype survey of AAV gene delivery via subconjunctival injection in mice

Additive effects of the combined expression of soluble forms of GAS1 and PTEN inhibiting glioblastoma growth

Improving therapeutic efficacy of IL-12 intratumoral gene electrotransfer through novel plasmid design and modified parameters

Metabolically stabilized double-stranded mRNA polyplexes

Scaffold-mediated delivery for non-viral mRNA vaccines

Characterization of abscopal effects of intratumoral electroporation-mediated IL-12 gene therapy

Nanosphere-mediated co-delivery of VEGF-A and PDGF-B genes for accelerating diabetic foot ulcers healing in rats

In vivo selection with lentiviral expression of Bcl2T69A/S70A/S87A mutant in hematopoietic stem cell-transplanted mice

AAV-mediated NT-3 overexpression protects cochleae against noise-induced synaptopathy

Rationally designed AAV2 and AAVrh8R capsids provide improved transduction in the retina and brain

Osteoinduction within BMP-2 transduced muscle tissue fragments with and without a fascia layer: implications for bone tissue engineering

Driving cars to the clinic for solid tumors

Evaluation of the Glypican 3 promoter for transcriptional targeting of hepatocellular carcinoma

In vitro evaluation of a lentiviral two-step transcriptional amplification system using GAL4FF transactivator for gene therapy applications in bone repair