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OALib Journal期刊
ISSN: 2333-9721
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ISSN Print: 1476-5594

ISSN Online:

主页: https://www.nature.com/onc

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Androgen receptor-modulatory microRNAs provide insight into therapy resistance and therapeutic targets in advanced prostate cancer

Upregulated claudin-1 expression promotes colitis-associated cancer by promoting β-catenin phosphorylation and activation in Notch/p-AKT-dependent manner

GPNMB augments Wnt-1 mediated breast tumor initiation and growth by enhancing PI3K/AKT/mTOR pathway signaling and β-catenin activity

Quaking orchestrates a post-transcriptional regulatory network of endothelial cell cycle progression critical to angiogenesis and metastasis

ROR1-CAVIN3 interaction required for caveolae-dependent endocytosis and pro-survival signaling in lung adenocarcinoma

NMIIA promotes tumor growth and metastasis by activating the Wnt/β-catenin signaling pathway and EMT in pancreatic cancer

Axitinib exposure triggers endothelial cells senescence through ROS accumulation and ATM activation

Addiction to DUSP1 protects JAK2V617F-driven polycythemia vera progenitors against inflammatory stress and DNA damage, allowing chronic proliferation

Pathogenic mutations in neurofibromin identifies a leucine-rich domain regulating glioma cell invasiveness

Non-murine models to investigate tumor-immune interactions in head and neck cancer

JMJD2 promotes acquired cisplatin resistance in non-small cell lung carcinoma cells

YAP-dependent induction of UHMK1 supports nuclear enrichment of the oncogene MYBL2 and proliferation in liver cancer cells

FDPS cooperates with PTEN loss to promote prostate cancer progression through modulation of small GTPases/AKT axis

Non-canonical HIF-1 stabilization contributes to intestinal tumorigenesis

Endogenous interaction profiling identifies DDX5 as an oncogenic coactivator of transcription factor Fra-1

UHRF1 promotes renal cell carcinoma progression through epigenetic regulation of TXNIP

BET bromodomain inhibition blocks the function of a critical AR-independent master regulator network in lethal prostate cancer

H19 lncRNA identified as a master regulator of genes that drive uterine leiomyomas

AKIP1 promotes early recurrence of hepatocellular carcinoma through activating the Wnt/β-catenin/CBP signaling pathway

MST1R kinase accelerates pancreatic cancer progression via effects on both epithelial cells and macrophages

Cancer-associated fibroblasts promote prostate cancer malignancy via metabolic rewiring and mitochondrial transfer

PARI (PARPBP) suppresses replication stress-induced myeloid differentiation in leukemia cells

Targeting AU-rich element-mediated mRNA decay with a truncated active form of the zinc-finger protein TIS11b/BRF1 impairs major hallmarks of mammary tumorigenesis

LPLUNC1 stabilises PHB1 by counteracting TRIM21-mediated ubiquitination to inhibit NF-κB activity in nasopharyngeal carcinoma

Distinctive requirement of PKCε in the control of Rho GTPases in epithelial and mesenchymally transformed lung cancer cells

Dissecting mechanisms of resistance to targeted drug combination therapy in human colorectal cancer

Tumor-associated macrophage-secreted 14-3-3ζ signals via AXL to promote pancreatic cancer chemoresistance

Cancer stem cell self-renewal as a therapeutic target in human oral cancer

The miR-186-3p/EREG axis orchestrates tamoxifen resistance and aerobic glycolysis in breast cancer cells

piRNA-823 delivered by multiple myeloma-derived extracellular vesicles promoted tumorigenesis through re-educating endothelial cells in the tumor environment

PDGFR-induced autocrine SDF-1 signaling in cancer cells promotes metastasis in advanced skin carcinoma

A high-throughput screen identifies the long non-coding RNA DRAIC as a regulator of autophagy

Identification and characterization of two novel oncogenic mTOR mutations

Inhibition of geranylgeranyl diphosphate synthase is a novel therapeutic strategy for pancreatic ductal adenocarcinoma

Low doses of decitabine improve the chemotherapy efficacy against basal-like bladder cancer by targeting cancer stem cells

LINC00162 confers sensitivity to 5-Aza-2′-deoxycytidine via modulation of an RNA splicing protein, HNRNPH1

Mitochondrial fission-induced mtDNA stress promotes tumor-associated macrophage infiltration and HCC progression

AKT drives SOX2 overexpression and cancer cell stemness in esophageal cancer by protecting SOX2 from UBR5-mediated degradation

Extracellular vesicle-dependent effect of RNA-binding protein IGF2BP1 on melanoma metastasis

MYB regulates the DNA damage response and components of the homology-directed repair pathway in human estrogen receptor-positive breast cancer cells

The anti-malarial drug chloroquine sensitizes oncogenic NOTCH1 driven human T-ALL to γ-secretase inhibition

LncRNA NORAD is repressed by the YAP pathway and suppresses lung and breast cancer metastasis by sequestering S100P

Impaired microRNA processing by DICER1 downregulation endows thyroid cancer with increased aggressiveness

ALK positively regulates MYCN activity through repression of HBP1 expression

Hepatitis B virus X protein promotes DNA damage propagation through disruption of liver polyploidization and enhances hepatocellular carcinoma initiation

Caspase-11 regulates the tumour suppressor function of STAT1 in a murine model of colitis-associated carcinogenesis

Microenvironmental oxygen pressure orchestrates an anti- and pro-tumoral γδ T cell equilibrium via tumor-derived exosomes

NOVA1 directs PTBP1 to hTERT pre-mRNA and promotes telomerase activity in cancer cells

Inhibition of TAZ contributes radiation-induced senescence and growth arrest in glioma cells

Inhibitors of ribosome biogenesis repress the growth of MYCN-amplified neuroblastoma

©2008-2017 OALib, Inc | Public user content licensed CC-BY 4.0 unless otherwise specified. OALib ISSN Online: 2333-9721 OALib ISSN Print: 2333-9705