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ISSN: 2333-9721
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ISSN Print: 1473-1150

ISSN Online:

主页: https://www.nature.com/tpj

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Is a pharmacogenomic panel useful to estimate the risk of oxaliplatin-related neurotoxicity in colorectal cancer patients?

DPYD*6 plays an important role in fluoropyrimidine toxicity in addition to DPYD*2A and c.2846A>T: a comprehensive analysis in 1254 patients

Candidate gene analyses for acute pain and morphine analgesia after pediatric day surgery: African American versus European Caucasian ancestry and dose prediction limits

A genome-wide association study of tramadol metabolism from post-mortem samples

Predicting antidepressant treatment outcome based on socioeconomic status and citalopram dose

Patient-provider communications about pharmacogenomic results increase patient recall of medication changes

Genetic association between CD96 locus and immunogenicity to anti-TNF therapy in Crohn’s disease

Impact of SLCO1B3 polymorphisms on clinical outcomes in lung allograft recipients receiving mycophenolic acid

An economic model of the cost-utility of pre-emptive genetic testing to support pharmacotherapy in patients with major depression in primary care

Precision dosing of warfarin: open questions and strategies

The effect of vitamin D pathway genes and deferasirox pharmacogenetics on liver iron in thalassaemia major patients

Prognostic role of genetic polymorphisms of the interleukin-6 signaling pathway in patients with severe heart failure

Warfarin loading dose guided by pharmacogenetics is effective and safe in cardioembolic stroke patients – a randomized, prospective study

Variants in vincristine pharmacodynamic genes involved in neurotoxicity at induction phase in the therapy of pediatric acute lymphoblastic leukemia

Identification of SAMD9L as a susceptibility locus for intravenous immunoglobulin resistance in Kawasaki disease by genome-wide association analysis

Prognostic impact of genetic variants of CYP19A1 and UGT2B17 in a randomized trial for endocrine-responsive postmenopausal breast cancer

Cost-effectiveness analysis of pharmacogenomics-guided clopidogrel treatment in Spanish patients undergoing percutaneous coronary intervention

A single nucleotide polymorphism of IL6-receptor is associated with response to tocilizumab in rheumatoid arthritis patients

Early modifications of circulating microRNAs levels in metastatic colorectal cancer patients treated with regorafenib

Genome-wide association study of antidepressant treatment resistance in a population-based cohort using health service prescription data and meta-analysis with GENDEP

Genetic polymorphisms in ABCG2 and CYP1A2 are associated with imatinib dose reduction in patients treated for gastrointestinal stromal tumors

Genetic polymorphisms associated with reactive oxygen species and blood pressure regulation

Genotype, phenotype, and medication recommendation agreement among commercial pharmacogenetic-based decision support tools

UGT1A1 polymorphisms associated with prolactin response in risperidone-treated children and adolescents with autism spectrum disorder

The in vitro functional analysis of single-nucleotide polymorphisms associated with growth hormone (GH) response in children with GH deficiency

Two common mutations within CYP2C19 affected platelet aggregation in Chinese patients undergoing PCI: a one-year follow-up study

HLA-C*12:02 is strongly associated with Xuesaitong-induced cutaneous adverse drug reactions

Frequency of vitamin K oxidoreductase complex subunit-1 (VKORC1) polymorphisms and warfarin dose management in patients with venous thromboembolism

An optimized prediction framework to assess the functional impact of pharmacogenetic variants

Whole genome sequencing identifies high-impact variants in well-known pharmacogenomic genes

Genome-wide association analysis of common genetic variants of resistant hypertension

Genetic markers in methotrexate treatments

Association between HLA-B*5901 and methazolamide-induced Stevens-Johnson syndrome/toxic epidermal necrolysis: a systematic review and meta-analysis

An African-specific profile of pharmacogene variants for rosuvastatin plasma variability: limited role for SLCO1B1 c.521T>C and ABCG2 c.421A>C

Association between SLCO1B1 T521C polymorphism and risk of statin-induced myopathy: a meta-analysis

Genome-wide enrichment of m6A-associated single-nucleotide polymorphisms in the lipid loci

Replication of the pharmacogenetic effect of rs678849 on buprenorphine efficacy in African–Americans with opioid use disorder

Genome-wide association study of response to tumour necrosis factor inhibitor therapy in rheumatoid arthritis

A genome-wide association and admixture mapping study of bronchodilator drug response in African Americans with asthma

BDNF Val66Met polymorphism and clinical response to antipsychotic treatment in schizophrenia and schizoaffective disorder patients: a meta-analysis

Iatrogenic hypertension: a bioinformatic analysis

Polymorphisms in CEP68 gene associated with risk of immediate selective reactions to non-steroidal anti-inflammatory drugs

A non-functional galanin receptor-2 in a multiple sclerosis patient

Genome-wide meta-analysis of SNP-by9-ACEI/ARB and SNP-by-thiazide diuretic and effect on serum potassium in cohorts of European and African ancestry

Pharmacogenetics of platinum-based chemotherapy: impact of DNA repair and folate metabolism gene polymorphisms on prognosis of non-small cell lung cancer patients

Evaluation of a clinical pharmacogenetics model to predict methotrexate response in patients with rheumatoid arthritis

Gamma-aminobutyric acid (GABA) receptors genes polymorphisms and risk for restless legs syndrome

Polymorphisms in cytochrome P450 are associated with extensive efavirenz pharmacokinetics and CNS toxicities in an HIV cohort in Botswana

Cross-ethnicity tagging SNPs for HLA alleles associated with adverse drug reaction

Variation within voltage-gated calcium channel genes and antipsychotic treatment response in a South African first episode schizophrenia cohort

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