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JGP | The Journal of General Physiology

ISSN Print: 1540-7748

ISSN Online:

主页: http://jgp.rupress.org/

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Known structures and unknown mechanisms of TMEM16 scramblases and channels

Accardi,Alessio,Alessio Accardi,Byoung-Cheol,Byoung-Cheol Lee,Falzone,Lee,Malvezzi,Maria E.,Maria E. Falzone,Mattia,Mattia Malvezzi

A privileged role for neuronal Na+ channels in regulating ventricular [Ca2+] and arrhythmias

DeAnalisa C.,DeAnalisa C. Jones,Eric A. Sobie,Gong,Jingqi Q.X.,Jingqi Q.X. Gong,Jones

A novel high-affinity inhibitor against the human ATP-sensitive Kir6.2 channel

Ramu,Xu,Yajamana,Yajamana Ramu,Yanping,Yanping Xu,Zhe Lu

One drug-sensitive subunit is sufficient for a near-maximal retigabine effect in KCNQ channels

Ammar,Caroline K.,Caroline K. Wang,Harley T.,Harley T. Kurata,Jingru,Jingru Li,Kim,Kurata,Li,Michael C.,Michael C. Yau,Pless,Robin Y.,Robin Y. Kim,Runying Y.,Runying Y. Yang,Stephan A.,Stephan A. Pless,Tarek,Tarek Ammar,Wang,Yang,Yau

Four drug-sensitive subunits are required for maximal effect of a voltage sensor–targeted KCNQ opener

Alice W.,Alice W. Wang,Caroline K.,Caroline K. Wang,Harley T.,Harley T. Kurata,Kurata,Michael C.,Michael C. Yau,Nazlee,Nazlee Sharmin,Pless,Runying Y.,Runying Y. Yang,Sharmin,Stephan A.,Stephan A. Pless,Wang,Yang,Yau

Influences: Experimenting with multidisciplinary training

Cheng,Heping (Peace),Heping (Peace) Cheng

Predicting voltage sensing

Caitlin,Caitlin Sedwick,Sedwick

Physiological CRAC channel activation and pore properties require STIM1 binding to all six Orai1 subunits

Lewis,Michelle,Michelle Yen,Richard S.,Richard S. Lewis,Yen

Molecular determination of claudin-15 organization and channel selectivity

Christopher,Christopher Weber,Fatemeh,Fatemeh Khalili-Araghi,Fuladi,Jinjing,Jinjing Zou,Khalili-Araghi,Le Shen,Li,Priyanka,Priyanka Samanta,Samanta,Shadi,Shadi Fuladi,Wang,Weber,Ye,Ye Li,Yitang,Yitang Wang,Zou

Shear elegance: A novel screen uncovers a mechanosensitive GPCR

Alexer T. Chesler,Lam,Ruby M.,Ruby M. Lam

Another way of seeing things

Caitlin,Caitlin Sedwick,Sedwick

The acid test for pH-dependent gating in cloned HV1 channels

León D. Islas

Correction: Otopetrin-1: A sour-tasting proton channel

DeSimone,I. Scott,I. Scott Ramsey,John A.,John A. DeSimone,Ramsey

The high-affinity calcium sensor synaptotagmin-7 serves multiple roles in regulated exocytosis

Anantharam,Arun,Arun Anantharam,Chon,Daniel D.,Daniel D. MacDougall,Hai,Hai Lin,Jackman,Jefferson D.,Jefferson D. Knight,Knight,Lin,MacDougall,Nara L.,Nara L. Chon,Skyler L.,Skyler L. Jackman,Zesen,Zesen Lin

Molecular and functional identification of a novel photopigment in Pecten ciliary photoreceptors

Arenas,Camila,Camila Pulido,Enrico,Enrico Nasi,Gerardo,Gerardo Malagón,Gomez,Malagón,María del Pilar,María del Pilar Gomez,Nasi,Oscar,Oscar Arenas,Osorno,Pulido,Tomás,Tomás Osorno

Coarse-grained molecular dynamics simulations reveal lipid access pathways in P-glycoprotein

Barreto-Ojeda,Corradi,D. Peter,D. Peter Tieleman,Estefania,Estefania Barreto-Ojeda,Gu,Ruo-Xu,Ruo-Xu Gu,Tieleman,Valentina,Valentina Corradi

Protein phosphorylation maintains the normal function of cloned human Cav2.3 channels

Alpdogan,Felix,Felix Neumaier,Hescheler,Jürgen,Jürgen Hescheler,Neumaier,Schneider,Serdar,Serdar Alpdogan,Toni,Toni Schneider

Mechanistic complexity of contractile dysfunction in hypertrophic cardiomyopathy

Michael,Michael Regnier,Regnier

Nebulin increases thin filament stiffness and force per cross-bridge in slow-twitch soleus muscle fibers

Granzier,Henk L.,Henk L. Granzier,Justin,Justin Kolb,Karam,Kolb,Li,Li Wang,Masataka Kawai,Tarek S.,Tarek S. Karam,Wang

Nebulin no longer nebulous

Caitlin,Caitlin Sedwick,Sedwick

Minimal molecular determinants of isoform-specific differences in efficacy in the HCN channel family

Alvarez-Baron,Baron,Baron Cha,Cha,Claudia P.,Claudia P. Alvarez-Baron,Klenchin,Vadim A.,Vadim A. Klenchin

Carriers, exchangers, and cotransporters in the first 100 years of the Journal of General Physiology

Jennings,Michael L.,Michael L. Jennings

A two-step docking site model predicting different short-term synaptic plasticity patterns

Alain Marty,Camila,Camila Pulido,Pulido

Bridging the gap toward understanding short-term synaptic plasticity

Caitlin,Caitlin Sedwick,Sedwick

Influences: Sodium channel excitement

Gail,Gail Mel,Mel

The ins and outs of vesicular monoamine transporters

Dana Yaffe,Forrest,Lucy R.,Lucy R. Forrest,Schuldiner,Shimon,Shimon Schuldiner

Correction: Lipid signaling to membrane proteins: From second messengers to membrane domains and adapter-free endocytosis

Anthony,Anthony Collins,Christine,Christine Deisl,Collins,Dai,Deisl,Donald W.,Donald W. Hilgemann,Fine,Gucan,Gucan Dai,Hilgemann,Lariccia,Magi,Michael,Michael Fine,Simona,Simona Magi,Vincenzo,Vincenzo Lariccia

The AKAP Cypher/Zasp contributes to β-adrenergic/PKA stimulation of cardiac CaV1.2 calcium channels

Can,Can Yuan,Catterall,Haijie,Haijie Yu,Ruth E.,Ruth E. Westenbroek,Westenbroek,William A.,William A. Catterall,Yu,Yuan

Exotic properties of a voltage-gated proton channel from the snail Helisoma trivolvis

Artinian,Cherny,DeCoursey,Deri,Deri Morgan,Liana R.,Liana R. Artinian,Morgan,Rehder,Sarah,Sarah Thomas,Smith,Susan M.E.,Susan M.E. Smith,Thomas,Thomas E.,Thomas E. DeCoursey,Vincent,Vincent Rehder,Vladimir V.,Vladimir V. Cherny

Intracellular and extracellular loops of LRRC8 are essential for volume-regulated anion channel function

Kevin,Kevin Strange,Strange,Toshiki,Toshiki Yamada,Yamada

The founding of Journal of General Physiology: Membrane permeation and ion selectivity

Bertil,Bertil Hille,Hille

The TMEM16A channel mediates the fast polyspermy block in Xenopus laevis

Anne E.,Anne E. Carlson,Carlson,Katherine L.,Katherine L. Wozniak,Lee,Maiwase,Maiwase Tembo,Miler T.,Miler T. Lee,Phelps,Tembo,Wesley A.,Wesley A. Phelps,Wozniak

Calcium-induced release of calcium in muscle: 50 years of work and the emerging consensus

Eduardo,Eduardo Ríos,Ríos

Improving the characterization of calcium channel gating pore currents with Stac3

Mohamed Chahine

The syndromic deafness mutation G12R impairs fast and slow gating in Cx26 hemichannels

Agustín D.,Agustín D. Martínez,Alvarez,Amaury,Amaury Pupo,Bernardo I.,Bernardo I. Pinto,Carlos,Carlos González,Contreras,Felipe,Felipe Villanelo,García,González,Gustavo F.,Gustavo F. Contreras,Isaac E.,Isaac E. García,Jorge E.,Jorge E. Contreras,Martínez,Osvaldo,Osvaldo Alvarez,Pinto,Pupo,Pérez-Acle,Ramon Latorre,Tomás,Tomás Pérez-Acle,Villanelo

Propofol’s paradox, explained

Caitlin,Caitlin Sedwick,Sedwick

Progress in understanding slow inactivation speeds up

Jian,Jian Payeh,Payeh

Correction: The relationship between form and function throughout the history of excitation–contraction coupling

Clara,Clara Franzini-Armstrong,Franzini-Armstrong

ATP is stored in lamellar bodies to activate vesicular P2X4 in an autocrine fashion upon exocytosis

Bareis,Charlotte,Charlotte Ziller,Christine,Christine Kranz,Ehinger,Elena,Elena Hecht,Fois,Giorgio,Giorgio Fois,Hecht,Jürgen,Jürgen Schymeinsky,Konstantin,Konstantin Ehinger,Kranz,Lara,Lara Bareis,Laura,Laura Staudenmaier,Manfred Frick,Schymeinsky,Staudenmaier,Veronika Eva,Veronika Eva Winkelmann,Winkelmann,Ziller

Membrane-mediated interaction drives mitochondrial ATPase assembly and cristae formation

Qiang Cui

A role for P2X4 receptors in lysosome function

Murrell-Lagnado,Ruth D.,Ruth D. Murrell-Lagnado

Junctional trafficking and restoration of retrograde signaling by the cytoplasmic RyR1 domain

Alexer,Alexer Polster,Beam,Bichraoui,Dilyana,Dilyana Filipova,Filipova,Hicham,Hicham Bichraoui,Joshua D.,Joshua D. Ohrtman,Kurt G.,Kurt G. Beam,Moua,Ohrtman,Ong,Ong Moua,Perni,Polster,Stefano,Stefano Perni,Symeon Papadopoulos

Dimerization of the voltage-sensing phosphatase controls its voltage-sensing and catalytic activity

Guillaume,Guillaume Soz,Karen,Karen Stengel,Kohout,Perrine,Perrine Royal,Rayaprolu,Royal,Soz,Stengel,Susy C.,Susy C. Kohout,Vamseedhar,Vamseedhar Rayaprolu

Second messenger molecules have a limited spread in olfactory cilia

Hiroko,Hiroko Takeuchi,Kurahashi,Takashi,Takashi Kurahashi,Takeuchi

The structure of Orco and its impact on our understanding of olfaction

Ana I.,Ana I. Domingos,Domingos,Frank Zufall

Different agonists induce distinct single-channel conductance states in TRPV1 channels

Canul-Sánchez,Enrique,Enrique Hernández-García,Hernández-Araiza,Hernández-García,Ileana,Ileana Hernández-Araiza,Itzel,Itzel Llorente,Jesús Aldair,Jesús Aldair Canul-Sánchez,León D. Islas,Llorente,Morales-Lázaro,Rosenbaum,Sara L.,Sara L. Morales-Lázaro,Tamara,Tamara Rosenbaum

Pore- and voltage sensor–targeted KCNQ openers have distinct state-dependent actions

Alice W.,Alice W. Wang,Caroline K.,Caroline K. Wang,Harley T.,Harley T. Kurata,Kurata,Lamothe,Runying Y.,Runying Y. Yang,Shawn M.,Shawn M. Lamothe,Wang,Yang

Anoctamin 5/TMEM16E facilitates muscle precursor cell fusion

Cui,H. Criss Hartzell,Jarred M.,Jarred M. Whitlock,Kuai,Kuai Yu,Whitlock,Yu,Yuan Yuan,Yuan Yuan Cui

Molecular determinants of pH regulation in the cardiac Na+–Ca2+ exchanger

Brian,Brian Kim,Goldhaber,John,Joshua I.,Joshua I. Goldhaber,Kim,Michela,Michela Ottolia,Olcese,Ottolia,Riccardo,Riccardo Olcese,Scott,Scott John

Estimating kinetic mechanisms with prior knowledge I: Linear parameter constraints

Autoosa,Autoosa Salari,Lorin S.,Lorin S. Milescu,Marco A.,Marco A. Navarro,Milescu,Mirela,Mirela Milescu,Navarro,Salari

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